New research reveals that patients who stop using popular GLP-1 drugs like Wegovy and Mounjaro can put back on reduced body mass far faster than those who stop conventional diet and exercise regimens.
Published data in a prominent health publication points out that while obese people can lose a large proportion of their body weight while using the jabs, the weight comes back at an average rate of 0.8 kg per month after stopping.
"Users using these treatments should be informed of the potential of quick weight regain when the therapy is stopped," warns researcher Dr. Susan Jebb.
This pace of recovery implies a reversion to starting mass within about a year and a half.
Weighing Therapies
The study, which reviewed dozens of studies involving over 9,000 of patients, contrasted the results of the injectable medications with conventional dieting.
Researchers point out that people who shed pounds through dieting typically have a more gradual weight regain—approximately 100 grams monthly—after stopping.
Explaining the Quick Regain
Doctors suggest the way of the jabs explains the amplified weight return.
These medications imitate a natural hormone called GLP-1, which helps regulate hunger.
"Artificially providing GLP-1 concentrations far above than the body's typical production might result in the system to generate a reduced amount of its endogenous GLP-1, and could lessen responsiveness to its actions," explained Dr. Adam Collins, a dietetics researcher.
"Withdrawal of this hormone supplement means appetite is unsuppressed, making binge eating far more likely."
A Chronic Disease?
Health authorities advise the injections for people with obesity-related health risks, accompanied by prescribed lifestyle changes.
A number of clinicians say that, given the high risk of relapse, the treatment is often long-term.
This perspective is supported by drug manufacturers, who state that the findings "highlight the chronic nature of excess weight," comparing it to managing conditions like high blood pressure.
User Experiences
Users who have stopped the jabs explain a sudden return of cravings.
"It felt as if something that goes on and I was suddenly starving," recalled an individual.
The struggle is exacerbated if patients have not established permanent lifestyle or habit changes during therapy.
Growing Interest
Recent estimates suggest that millions of people in the UK have used these injections in the last 12 months, with desire continuing to grow.
- Adoption is greater among females than males.
- The middle-aged demographic shows the highest level of interest.
- A large proportion obtain the medications through private healthcare rather than public health services.
In conclusion, experts emphasize that while GLP-1 drugs are potent agents for shedding pounds, they are not a permanent solution and long-term success relies on ongoing lifestyle management.
